Perinatal Infections

Perinatal Infections...

TORCH

Toxoplasmosis
Other (syphillis) - I always hate when "other" is one!
Rubella
Cytomegalovirus
Herpes










Source: Hardcore Pathology by Wahl

PANCE: Buzz Words

When studying for the PANCE it is difficult to "know it all" - sometimes you need some helpful hints to jog your memory or lead you in the direction of a likely answer....  The following list contains some word association stuff that may help for which organisms in pneumonia are most common in particular populations. Word association is no substitute for knowing and understanding the clinical scenario, but it may help you narrow down the options.

I will put a list here... quiz yourself (see below for answers):

Which pneumonia organisms would you match with the following patient populations or buzz words?

1. ETOH 
2. COPD
3. Air conditioners/cooling systems
4. Cystic fibrosis
5. Asplenic
6. College
7. Leukemia
8. Kids < 1 yo
9. Kids > 2 yo

 Answers:

1. ETOH = Klebsiella
2. COPD = Haemophilus influenza (H.flu)
3. Air conditioners/cooling systems = Legionella
4. Cystic fibrosis = Pseudomonas
5. Asplenic = encapsulated organisms (strep pneumo/H.flu)
6. College = mycoplasm pneumo or chlamydia pneumo (longer prodrome, sore throat, hoarseness)
7. Leukemia = fungus
8. Kids < 1 yo = RSV
9. Kids > 2 yo = parainfluenza virus

Antibiotics Help Packet (Free)

Dr. Philpott-Howard (Dept of Infectious Dz) came up with this incredible Antibiotics packet for his medical students. Hope it is as helpful to you as it has been for me!

ANTIBIOTICS HELP PACKET
Here is a new link that was sent to me (Thanks Rachael!): 
http://www.readbag.com/francoverde-ms3-misc-antibioticsforyear3medics

PANCE REVIEW: Spirochetal infections

Those pesky spirochetal infections:

	LYME	ROCKY MNT SPOTTED FEVER
General	Borrelia burgdorferi, deer tick must feed for 24-36hrs to pass dz, *Most common vector born-dz	Rickettsia rickettsii (wood tick), common in eastern US
Clinical	Stage 1:local infx (7-10d after bite) - erythema migrans "bull's eye", flu-like sx in 50% pts, Stage 2: early dissemination - HA, stiff neck, malaise, fatigue, MS sx, cardiac sx in 20% cases, Stage 3:late persistent infx, MSD, central/perip NS	fever/chills/ N/V, insomnia can develop in 2-14 days, face is flushed and conjunctiva injected, small rash develops on extremities
Lab	antibody detection (immunoflu assay or ELISA), western blot to confirm, Ig M wanes after 6-8 wks, IgG can be indefinite, high likelihood of false+	leukocytosis, thrombocytopenia, hypONa+, proteinuria, hematuria, transient rise in bili, rise in antibody titers in 2nd wk, CSF = pleocytosis, hypocorrhachia
Tx	doxy for erythma migrans or lyme, NSAIDS, prevention	mild, untx cases wane in 2wks, doxy or chloramphenicol hasten recovery, poor outcome for advanced age